Radicular cyst in primary dentition showing angiolymphoid hyperplasia with eosinophilia (ALHE)-like features: An immunohistochemical study

The microscopical diagnosis of radicular cyst (RC) is straightforward; nonetheless, in some cases with unusual histopathological features, strict clinicopathological correlation necessary to achieve the correct diagnosis. We report a case 5-year-old girl was referred presenting extensive carious lesion tooth #55, associated vestibular sinus tract. Medical history revealed allergic asthma After clinical and imaginological exams, deciduous extracted. Microscopically, soft tissue attached root showed typical RC features; however, cystic capsule, lymphoid follicles vascular networks (lined by epithelioid endothelial cells) surrounded numerous eosinophils, were observed. Immunohistochemistry, through CD3, CD20, CD34 alpha-smooth muscle actin antibodies, highlighted these findings. Moreover, CD1a CD207 negative. To best our knowledge, this first showing angiolymphoid hyperplasia eosinophilia (ALHE)-like features.